News & Insights

Cardno ChemRisk publishes article in toxicology and pharmacology journal

The article illustrates through case studies how mathematical modeling can be used to determine BAC retrospectively at a given time point for forensic analyses. Using this approach, which combines modeling of alcohol metabolism and post-mortem alcohol generation considerations when necessary, forensic specialists can:

  • Accurately back-calculate BAC at a given time point using real-life consumption patterns (e.g., multiple drinks over time, different types of drinks);
  • Accurately estimate BAC based on individual characteristics (e.g., age, sex, height, weight); and
  • Estimate the contribution of alcohol generation to the measured BAC after death.
  • This study provides information for standardizing BAC determination in forensic toxicology, while minimizing real world case uncertainties.

The article’s authors include: Dallas M. Cowan, PhD, CIH, DABT; Brent L. Finley, PhD; Ernest S. Fung, PhD; Joshua R. Maskrey; Paul K. Scott; Tyler A. Woods; and Lisa M. Stabryla.

Regulatory Toxicology and Pharmacology is the official journal of the International Society for Regulatory Toxicology and Pharmacology. The journal presents articles concerned with regulatory decisions and with interpreting scientific knowledge that influences regulatory decisions.

Read the abstract. You can find more information about Regulatory Toxicology and Pharmacology on the journal’s website.

For more information contact:

Dallas Cowan, PhD, CIH, DABT
Managing Health Scientist
Phone: + 1 949-616-3782
dallas.cowan@cardno.com